SPDR S&P Biotech ETF (XBI)
In seeking to track the performance of the S&P Biotechnology Select Industry Index (the "index"), the fund employs a sampling strategy. It generally invests substantially all, but at least 80%, of its total assets in the securities comprising the index. The index represents the biotechnology segment of the S&P Total Market Index ("S&P TMI").
$8.03B
Jan 31, 2006
$0.00
Sector weights (10)
Health Care Select Sector SPDR Fund
XLV
100%
Utilities Select Sector SPDR Fund
XLU
0%
Technology Select Sector SPDR Fund
XLK
0%
The Real Estate Select Sector SPDR Fund
XLRE
0%
Industrial Select Sector SPDR Fund
XLI
0%
Financial Select Sector SPDR Fund
XLF
0%
Energy Select Sector SPDR Fund
XLE
0%
Consumer Discretionary Select Sector SPDR Fund
XLY
0%
Communication Services Select Sector SPDR Fund
XLC
0%
Materials Select Sector SPDR Fund
XLB
0%
ETF Constituents (124)
Exact Sciences Corporation
EXAS
3.75%
United Therapeutics Corporation
UTHR
3.186%
Gilead Sciences, Inc.
GILD
3.186%
AbbVie Inc.
ABBV
3.025%
Regeneron Pharmaceuticals, Inc.
REGN
2.885%
Alnylam Pharmaceuticals, Inc.
ALNY
2.855%
Amgen Inc.
AMGN
2.828%
BioMarin Pharmaceutical Inc.
BMRN
2.664%
Sarepta Therapeutics, Inc.
SRPT
2.641%
Natera, Inc.
NTRA
2.627%
Vertex Pharmaceuticals Incorporated
VRTX
2.566%
Viking Therapeutics, Inc.
VKTX
2.559%
Incyte Corporation
INCY
2.493%
Biogen Inc.
BIIB
2.271%
Neurocrine Biosciences, Inc.
NBIX
2.073%
Cytokinetics, Incorporated
CYTK
2.054%
Vaxcyte, Inc.
PCVX
1.507%
Apellis Pharmaceuticals, Inc.
APLS
1.412%
Moderna, Inc.
MRNA
1.357%
Madrigal Pharmaceuticals, Inc.
MDGL
1.267%
Exelixis, Inc.
EXEL
1.252%
BridgeBio Pharma, Inc.
BBIO
1.195%
Blueprint Medicines Corporation
BPMC
1.141%
Insmed Incorporated
INSM
1.135%
Ionis Pharmaceuticals, Inc.
IONS
1.133%
Halozyme Therapeutics, Inc.
HALO
1.098%
Revolution Medicines, Inc.
RVMD
1.093%
Krystal Biotech, Inc.
KRYS
1.093%
TG Therapeutics, Inc.
TGTX
1.045%
Biohaven Pharmaceutical Holding Company Ltd.
BHVN
1.017%
Ultragenyx Pharmaceutical Inc.
RARE
0.986%
Iovance Biotherapeutics, Inc.
IOVA
0.943%
Arcellx, Inc.
ACLX
0.867%
SpringWorks Therapeutics, Inc.
SWTX
0.858%
Crinetics Pharmaceuticals, Inc.
CRNX
0.81%
Nuvalent, Inc.
NUVL
0.763%
Amicus Therapeutics, Inc.
FOLD
0.757%
Celldex Therapeutics, Inc.
CLDX
0.739%
ACADIA Pharmaceuticals Inc.
ACAD
0.696%
Dyne Therapeutics, Inc.
DYN
0.69%
Immunovant, Inc.
IMVT
0.671%
ADMA Biologics, Inc.
ADMA
0.649%
Vera Therapeutics, Inc.
VERA
0.633%
Avidity Biosciences, Inc.
RNA
0.627%
IDEAYA Biosciences, Inc.
IDYA
0.616%
Intellia Therapeutics, Inc.
NTLA
0.589%
Geron Corporation
GERN
0.589%
Kymera Therapeutics, Inc.
KYMR
0.586%
Beam Therapeutics Inc.
BEAM
0.55%
Twist Bioscience Corporation
TWST
0.547%
Denali Therapeutics Inc.
DNLI
0.538%
BioCryst Pharmaceuticals, Inc.
BCRX
0.53%
Ardelyx, Inc.
ARDX
0.512%
Catalyst Pharmaceuticals, Inc.
CPRX
0.511%
Rhythm Pharmaceuticals, Inc.
RYTM
0.508%
Dynavax Technologies Corporation
DVAX
0.491%
Syndax Pharmaceuticals, Inc.
SNDX
0.485%
Agios Pharmaceuticals, Inc.
AGIO
0.475%
Arrowhead Pharmaceuticals, Inc.
ARWR
0.468%
Janux Therapeutics, Inc.
JANX
0.463%
Nurix Therapeutics, Inc.
NRIX
0.459%
PTC Therapeutics, Inc.
PTCT
0.451%
Akero Therapeutics, Inc.
AKRO
0.451%
Veracyte, Inc.
VCYT
0.45%
Protagonist Therapeutics, Inc.
PTGX
0.445%
Novavax, Inc.
NVAX
0.431%
Keros Therapeutics, Inc.
KROS
0.428%
Vericel Corporation
VCEL
0.425%
Mirum Pharmaceuticals, Inc.
MIRM
0.403%
Arcutis Biotherapeutics, Inc.
ARQT
0.393%
Soleno Therapeutics, Inc.
SLNO
0.372%
Myriad Genetics, Inc.
MYGN
0.357%
Kura Oncology, Inc.
KURA
0.344%
CareDx, Inc
CDNA
0.343%
Recursion Pharmaceuticals, Inc.
RXRX
0.338%
Praxis Precision Medicines, Inc.
PRAX
0.328%
Rocket Pharmaceuticals, Inc.
RCKT
0.31%
Day One Biopharmaceuticals, Inc.
DAWN
0.3%
MannKind Corporation
MNKD
0.293%
Viridian Therapeutics, Inc.
VRDN
0.292%
Travere Therapeutics, Inc.
TVTX
0.291%
Summit Therapeutics Inc.
SMMT
0.284%
Cogent Biosciences, Inc.
COGT
0.273%
Cullinan Oncology, Inc.
CGEM
0.264%
AnaptysBio, Inc.
ANAB
0.255%
Ironwood Pharmaceuticals, Inc.
IRWD
0.252%
Sana Biotechnology, Inc.
SANA
0.246%
Avid Bioservices, Inc.
CDMO
0.231%
Immunome, Inc.
IMNM
0.221%
Arcus Biosciences, Inc.
RCUS
0.216%
Arcturus Therapeutics Holdings Inc.
ARCT
0.208%
ImmunityBio, Inc.
IBRX
0.207%
4D Molecular Therapeutics, Inc.
FDMT
0.204%
Altimmune, Inc.
ALT
0.191%
Relay Therapeutics, Inc.
RLAY
0.173%
Astria Therapeutics, Inc.
ATXS
0.173%
Olema Pharmaceuticals, Inc.
OLMA
0.172%
Disc Medicine, Inc.
IRON
0.172%
89bio, Inc.
ETNB
0.17%
REGENXBIO Inc.
RGNX
0.169%
Corbus Pharmaceuticals Holdings, Inc.
CRBP
0.167%
Stoke Therapeutics, Inc.
STOK
0.166%
Anavex Life Sciences Corp.
AVXL
0.164%
Vir Biotechnology, Inc.
VIR
0.16%
ORIC Pharmaceuticals, Inc.
ORIC
0.158%
Scholar Rock Holding Corporation
SRRK
0.152%
Allogene Therapeutics, Inc.
ALLO
0.143%
ARS Pharmaceuticals, Inc.
SPRY
0.14%
C4 Therapeutics, Inc.
CCCC
0.14%
Sage Therapeutics, Inc.
SAGE
0.133%
Ocugen, Inc.
OCGN
0.131%
MiMedx Group, Inc.
MDXG
0.122%
Fate Therapeutics, Inc.
FATE
0.121%
Verve Therapeutics, Inc.
VERV
0.118%
Tango Therapeutics, Inc.
TNGX
0.115%
Editas Medicine, Inc.
EDIT
0.109%
Savara Inc.
SVRA
0.087%
Scilex Holding Company
SCLX
0.081%
Voyager Therapeutics, Inc.
VYGR
0.078%
Humacyte, Inc.
HUMA
0.078%
iTeos Therapeutics, Inc.
ITOS
0.077%
Alector, Inc.
ALEC
0.069%
Heron Therapeutics, Inc.
HRTX
0.065%
Cabaletta Bio, Inc.
CABA
0.064%
Sector weights (10)
Health Care Select Sector SPDR Fund
XLV
100%
Utilities Select Sector SPDR Fund
XLU
0%
Technology Select Sector SPDR Fund
XLK
0%
The Real Estate Select Sector SPDR Fund
XLRE
0%
Industrial Select Sector SPDR Fund
XLI
0%
Financial Select Sector SPDR Fund
XLF
0%
Energy Select Sector SPDR Fund
XLE
0%
Consumer Discretionary Select Sector SPDR Fund
XLY
0%
Communication Services Select Sector SPDR Fund
XLC
0%
Materials Select Sector SPDR Fund
XLB
0%
ETF Constituents (124)
Exact Sciences Corporation
EXAS
3.75%
United Therapeutics Corporation
UTHR
3.186%
Gilead Sciences, Inc.
GILD
3.186%
AbbVie Inc.
ABBV
3.025%
Regeneron Pharmaceuticals, Inc.
REGN
2.885%
Alnylam Pharmaceuticals, Inc.
ALNY
2.855%
Amgen Inc.
AMGN
2.828%
BioMarin Pharmaceutical Inc.
BMRN
2.664%
Sarepta Therapeutics, Inc.
SRPT
2.641%
Natera, Inc.
NTRA
2.627%
Vertex Pharmaceuticals Incorporated
VRTX
2.566%
Viking Therapeutics, Inc.
VKTX
2.559%
Incyte Corporation
INCY
2.493%
Biogen Inc.
BIIB
2.271%
Neurocrine Biosciences, Inc.
NBIX
2.073%
Cytokinetics, Incorporated
CYTK
2.054%
Vaxcyte, Inc.
PCVX
1.507%
Apellis Pharmaceuticals, Inc.
APLS
1.412%
Moderna, Inc.
MRNA
1.357%
Madrigal Pharmaceuticals, Inc.
MDGL
1.267%
Exelixis, Inc.
EXEL
1.252%
BridgeBio Pharma, Inc.
BBIO
1.195%
Blueprint Medicines Corporation
BPMC
1.141%
Insmed Incorporated
INSM
1.135%
Ionis Pharmaceuticals, Inc.
IONS
1.133%
Halozyme Therapeutics, Inc.
HALO
1.098%
Revolution Medicines, Inc.
RVMD
1.093%
Krystal Biotech, Inc.
KRYS
1.093%
TG Therapeutics, Inc.
TGTX
1.045%
Biohaven Pharmaceutical Holding Company Ltd.
BHVN
1.017%
Ultragenyx Pharmaceutical Inc.
RARE
0.986%
Iovance Biotherapeutics, Inc.
IOVA
0.943%
Arcellx, Inc.
ACLX
0.867%
SpringWorks Therapeutics, Inc.
SWTX
0.858%
Crinetics Pharmaceuticals, Inc.
CRNX
0.81%
Nuvalent, Inc.
NUVL
0.763%
Amicus Therapeutics, Inc.
FOLD
0.757%
Celldex Therapeutics, Inc.
CLDX
0.739%
ACADIA Pharmaceuticals Inc.
ACAD
0.696%
Dyne Therapeutics, Inc.
DYN
0.69%
Immunovant, Inc.
IMVT
0.671%
ADMA Biologics, Inc.
ADMA
0.649%
Vera Therapeutics, Inc.
VERA
0.633%
Avidity Biosciences, Inc.
RNA
0.627%
IDEAYA Biosciences, Inc.
IDYA
0.616%
Intellia Therapeutics, Inc.
NTLA
0.589%
Geron Corporation
GERN
0.589%
Kymera Therapeutics, Inc.
KYMR
0.586%
Beam Therapeutics Inc.
BEAM
0.55%
Twist Bioscience Corporation
TWST
0.547%
Denali Therapeutics Inc.
DNLI
0.538%
BioCryst Pharmaceuticals, Inc.
BCRX
0.53%
Ardelyx, Inc.
ARDX
0.512%
Catalyst Pharmaceuticals, Inc.
CPRX
0.511%
Rhythm Pharmaceuticals, Inc.
RYTM
0.508%
Dynavax Technologies Corporation
DVAX
0.491%
Syndax Pharmaceuticals, Inc.
SNDX
0.485%
Agios Pharmaceuticals, Inc.
AGIO
0.475%
Arrowhead Pharmaceuticals, Inc.
ARWR
0.468%
Janux Therapeutics, Inc.
JANX
0.463%
Nurix Therapeutics, Inc.
NRIX
0.459%
PTC Therapeutics, Inc.
PTCT
0.451%
Akero Therapeutics, Inc.
AKRO
0.451%
Veracyte, Inc.
VCYT
0.45%
Protagonist Therapeutics, Inc.
PTGX
0.445%
Novavax, Inc.
NVAX
0.431%
Keros Therapeutics, Inc.
KROS
0.428%
Vericel Corporation
VCEL
0.425%
Mirum Pharmaceuticals, Inc.
MIRM
0.403%
Arcutis Biotherapeutics, Inc.
ARQT
0.393%
Soleno Therapeutics, Inc.
SLNO
0.372%
Myriad Genetics, Inc.
MYGN
0.357%
Kura Oncology, Inc.
KURA
0.344%
CareDx, Inc
CDNA
0.343%
Recursion Pharmaceuticals, Inc.
RXRX
0.338%
Praxis Precision Medicines, Inc.
PRAX
0.328%
Rocket Pharmaceuticals, Inc.
RCKT
0.31%
Day One Biopharmaceuticals, Inc.
DAWN
0.3%
MannKind Corporation
MNKD
0.293%
Viridian Therapeutics, Inc.
VRDN
0.292%
Travere Therapeutics, Inc.
TVTX
0.291%
Summit Therapeutics Inc.
SMMT
0.284%
Cogent Biosciences, Inc.
COGT
0.273%
Cullinan Oncology, Inc.
CGEM
0.264%
AnaptysBio, Inc.
ANAB
0.255%
Ironwood Pharmaceuticals, Inc.
IRWD
0.252%
Sana Biotechnology, Inc.
SANA
0.246%
Avid Bioservices, Inc.
CDMO
0.231%
Immunome, Inc.
IMNM
0.221%
Arcus Biosciences, Inc.
RCUS
0.216%
Arcturus Therapeutics Holdings Inc.
ARCT
0.208%
ImmunityBio, Inc.
IBRX
0.207%
4D Molecular Therapeutics, Inc.
FDMT
0.204%
Altimmune, Inc.
ALT
0.191%
Relay Therapeutics, Inc.
RLAY
0.173%
Astria Therapeutics, Inc.
ATXS
0.173%
Olema Pharmaceuticals, Inc.
OLMA
0.172%
Disc Medicine, Inc.
IRON
0.172%
89bio, Inc.
ETNB
0.17%
REGENXBIO Inc.
RGNX
0.169%
Corbus Pharmaceuticals Holdings, Inc.
CRBP
0.167%
Stoke Therapeutics, Inc.
STOK
0.166%
Anavex Life Sciences Corp.
AVXL
0.164%
Vir Biotechnology, Inc.
VIR
0.16%
ORIC Pharmaceuticals, Inc.
ORIC
0.158%
Scholar Rock Holding Corporation
SRRK
0.152%
Allogene Therapeutics, Inc.
ALLO
0.143%
ARS Pharmaceuticals, Inc.
SPRY
0.14%
C4 Therapeutics, Inc.
CCCC
0.14%
Sage Therapeutics, Inc.
SAGE
0.133%
Ocugen, Inc.
OCGN
0.131%
MiMedx Group, Inc.
MDXG
0.122%
Fate Therapeutics, Inc.
FATE
0.121%
Verve Therapeutics, Inc.
VERV
0.118%
Tango Therapeutics, Inc.
TNGX
0.115%
Editas Medicine, Inc.
EDIT
0.109%
Savara Inc.
SVRA
0.087%
Scilex Holding Company
SCLX
0.081%
Voyager Therapeutics, Inc.
VYGR
0.078%
Humacyte, Inc.
HUMA
0.078%
iTeos Therapeutics, Inc.
ITOS
0.077%
Alector, Inc.
ALEC
0.069%
Heron Therapeutics, Inc.
HRTX
0.065%
Cabaletta Bio, Inc.
CABA
0.064%